Corticosteroid induced, HHV-8 positive Kaposi’s sarcoma in a non-HIV elderly patient

  • Gh Mohiuddin Wani SKIMS-MCH,BEMINA SRINAGAR JAMU AND KASHMIR
  • Sheikh Manzoor Ahmad Sheri-Kashmir Institute of Medical Sciences (SKIMS) Srinager, Kashmir, India
  • Seema Qayoom Sheri-Kashmir Institute of Medical Sciences (SKIMS) Srinager, Kashmir, India
  • Bilquees Khursheed Sheri-Kashmir Institute of Medical Sciences (SKIMS) Srinager, Kashmir, India
  • A. R. Khan Government Medical College Srinager, Kashmir, India
Keywords: Kaposi sarcoma, corticosteroids, HHV-8, HIV/AIDS

Abstract

DOI: http://dx.doi.org/10.5915/44-1-9317

Kaposi’s sarcoma (KS) was first described in 1872 by Moritz Kaposi. In 1994, Chang et al. first identified DNA sequences corresponding to human herpesvirus-8 (HHV-8) in AIDS-associated Kaposi sarcoma biopsies. It is now believed that presence of HHV-8 is necessary but not sufficient to cause KS. Other factors like immunosuppressive therapy also play a role. We describe an HIV-negative elderly patient who developed KS of skin and mucous membrane after prolonged use of corticosteroids for knee pain. The patient was positive for HHV-8.

Author Biographies

Gh Mohiuddin Wani, SKIMS-MCH,BEMINA SRINAGAR JAMU AND KASHMIR

M.D., Senior resident

Department of Dermatology, Venereology and Leprosy

Sheri-Kashmir Institute of Medical Sciences (SKIMS)

 

Sheikh Manzoor Ahmad, Sheri-Kashmir Institute of Medical Sciences (SKIMS) Srinager, Kashmir, India

M.D.

Department of Dermatology, Venereology and Leprosy

Sheri-Kashmir Institute of Medical Sciences (SKIMS)

Srinager, Kashmir, India


Seema Qayoom, Sheri-Kashmir Institute of Medical Sciences (SKIMS) Srinager, Kashmir, India

M.D.

Department of Dermatology, Venereology and Leprosy

Sheri-Kashmir Institute of Medical Sciences (SKIMS)

Srinager, Kashmir, India


Bilquees Khursheed, Sheri-Kashmir Institute of Medical Sciences (SKIMS) Srinager, Kashmir, India

MBBS

Department of Dermatology, Venereology and Leprosy

Sheri-Kashmir Institute of Medical Sciences (SKIMS)

Srinager, Kashmir, India

 

A. R. Khan, Government Medical College Srinager, Kashmir, India

M.D.

Department of Pathology

Government Medical College

Srinager, Kashmir, India

 

Published
2012-08-15
Section
Case Reports