Efficacy of Povidone Iodine in Treatment of Active Chronic Suppurative Otitis Media

Ahmed M. Al-Abbasi


This is a double-blind prospective study done in Basra, Iraq, from February 1 to October 31, 2005.

Forty-eight patients with active chronic suppurative otitis media (CSOM)
were included in this study. Full histories were obtained. Otological examinations and ear swabs for culture were done. Pure tone audiometry (PTA) was performed before and two weeks after treatment. All the patients studied were treated systemically by an appropriate dose of amoxicillin.

The most common isolated organism was staphylococcus aureus (25%), followed by pseudomonas aeroginosa (18.8%) and streptococcus pneumoniae (18.8%).

Povidone iodine (betadine) 5% solution, neomycin dexamethasone (neodexone) drops, and normal saline 0.9% were used as local therapy (ear drops) randomly for three equally divided groups of patients.

Complete improvement occurred in 81% of the patients using povidone iodine ear drops, compared with 69% using neomycin-dexamethasone drops and only 25% using normal saline drops. Further, improvement using povidone iodine occurred earlier than improvement using neomycin-dexamethasone and normal saline ear drops.

No complications were detected as a result of any of the above treatment modalities.



Povidone iodine; chronic suppurative otitis media

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DOI: https://doi.org/10.5915/38-3-5986

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