Acute Metoclopramide Toxicity in Children
DOI:
https://doi.org/10.5915/23-4-15427Keywords:
Gastroenteritis, metoclopramide, vomiting, extrapyramidal symptomsAbstract
DOI: http://dx.doi.org/10.5915/23-4-15427
Vomiting is a common symptom in children and is usually treated with phenothiazines. A new dopamine antagonist, metoclopramide, considered relatively safe, is widely used as antiemetic. The development of extrapyramida symptoms is a well known manifestation of phenothiazine toxicity. During an epidemic of gastroenteritis, we encountered 18 patients who had received metoclopramide and developed extrapyramidal symptoms. All patients improved with diphenhydramine therapy. Our experience suggests that the development of extrapyramidal symptoms after intake of metoclopramide may not be uncommon.
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Published
1991-10-01
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Review Articles
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