Neurologic Complications of Progressive Systemic Sclerosis
Neurologic manifestations/complications of systemic scleroderma have received less attention in the literature than cardiac, pulmonary or gastrointestinal manifestations. We describe briefly three autopsied and proven cases of progressive systemic sclerosis in which there had developed prominent neurologic symptoms and signs, and discuss the relationship of those symptoms and signs with progressive systemic sclerosis. A review of neurologic complications is presented specifically to direct the attention of physicians to such symptoms which may later result in increased reporting of neurologic symptoms and signs. Already there is increased awareness due to reports of conditions such as trigeminal neuropathy and myopathy in more recent years. Cerebral, and specifically cerebrovascular, manifestations may be recognized more frequently in the future. A brief note of etiopathology and treatment is also mentioned.
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).