Genetic Markers in Duodenal Ulcer Disease

  • M Mujahid Ali Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India
  • C M Habibullah Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India
  • M Salahuddin Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India
Keywords: Duodenal ulcer, genetic markers

Abstract

DOI: http://dx.doi.org/10.5915/20-2-13284

A study has been carried out on 100 endoscopically proven duodenal ulcer patients and in 100 healthy controls to examine the role of genetic factors in the development of duodenal ulcer disease. Serum pepsinogen levels, serum alpha-J-antitrypsin, haptoglobin phenotyping and ABO blood groups served as genetic markers. Hyperpepsinogenemia, deficiency of alpha-1-antitrypsin, haptoglobin 2-2 typing and 'O' blood group were found to be associated with duodenal ulcer disease.

Author Biographies

M Mujahid Ali, Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India

Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India

Ph.D.

C M Habibullah, Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India

Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India

M.D., D.M.

M Salahuddin, Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India

Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India

M.Sc.

Published
1988-07-01
Section
Original Articles