Genetic Markers in Duodenal Ulcer Disease

Authors

  • M Mujahid Ali Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India
  • C M Habibullah Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India
  • M Salahuddin Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India

DOI:

https://doi.org/10.5915/20-3-13284

Keywords:

Duodenal ulcer, genetic markers

Abstract

DOI: http://dx.doi.org/10.5915/20-2-13284

A study has been carried out on 100 endoscopically proven duodenal ulcer patients and in 100 healthy controls to examine the role of genetic factors in the development of duodenal ulcer disease. Serum pepsinogen levels, serum alpha-J-antitrypsin, haptoglobin phenotyping and ABO blood groups served as genetic markers. Hyperpepsinogenemia, deficiency of alpha-1-antitrypsin, haptoglobin 2-2 typing and 'O' blood group were found to be associated with duodenal ulcer disease.

Author Biographies

M Mujahid Ali, Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India

Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India

Ph.D.

C M Habibullah, Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India

Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India

M.D., D.M.

M Salahuddin, Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India

Department of Gastroenteralogy, Osmania General Hospital, Hyderabad, (A.P.), India

M.Sc.

Downloads

Published

1988-07-01

Issue

Vol. 20 No. 3 (1988)

Section

Original Articles

License

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).