Genetic Markers in Duodenal Ulcer Disease

M Mujahid Ali, C M Habibullah, M Salahuddin



A study has been carried out on 100 endoscopically proven duodenal ulcer patients and in 100 healthy controls to examine the role of genetic factors in the development of duodenal ulcer disease. Serum pepsinogen levels, serum alpha-J-antitrypsin, haptoglobin phenotyping and ABO blood groups served as genetic markers. Hyperpepsinogenemia, deficiency of alpha-1-antitrypsin, haptoglobin 2-2 typing and 'O' blood group were found to be associated with duodenal ulcer disease.


Duodenal ulcer; genetic markers

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