The Presentation of Gastric Cancer in the Kashmiri Native: An Analysis of 850 Cases

  • Hamid A Durrani Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India
  • G M Malik Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India
  • N M Tikku Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India
  • Mehraj Ud Din Khan Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India
  • Inder Gupta Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India
  • Masarrat Durrani Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India
Keywords: Gastric cancer, adenocarcinoma malignant ulcer, early gastric cancer, e1iology of gastric cancer, nitrates, upper gastrointestinal tract

Abstract

DOI: http://dx.doi.org/10.5915/20-2-

Gastric cancer is the most frequent gastrointestinal neoplasm in the native population of Kashmir valley situated in the mountains of North-West India. The prevalence rate in other population groups in India is much lower.

 

The study is a comprehensive analysis of 850 cases diagnosed in the last five years at one teaching-cum-referral center. Of these, 82% were males and 18% were females; 62% were smokers and 38% were non-smokers; 60% of patients belonged to the age group 41-60 years.

Endoscopic appearances were classified as: nodular mass 47%, polypoid mass 20%, malignant ulcer 10%, infilterative lesion 8%, rounded tumor mass 8%, linitis plastica 5% and 'early carcinoma' 2%. On histopathological typing; 79% of the lesions were adenocarcinomes, 8% mucoid carcinomas, 8% leiomyosarcomes, 4% schirrous carcinomas, and 1% reticulum cell sarcomas.

The possible etiological factors peculiar to the dietary constituents, including the consumption of hot salted tea and of a particular leafy vegetable, are singled out. The genetic factors may have an important role in the etiology of stomach cancer in this high risk group.

Author Biographies

Hamid A Durrani, Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India

M.D., F.A.C.G.

Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India

G M Malik, Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India

M.D.

Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India

N M Tikku, Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India

M.D.

Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India

Mehraj Ud Din Khan, Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India

M.D.

Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India

Inder Gupta, Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India

M.D.

Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India

Masarrat Durrani, Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India

M.B.B.S.

Division of Gastroenterology, Department of Medicine, Government Medical College, Srinagar, Kashmir, India

Published
1988-04-01
Section
Original Articles