The Presentation of Gastric Cancer in the Kashmiri Native: An Analysis of 850 Cases
Gastric cancer is the most frequent gastrointestinal neoplasm in the native population of Kashmir valley situated in the mountains of North-West India. The prevalence rate in other population groups in India is much lower.
The study is a comprehensive analysis of 850 cases diagnosed in the last five years at one teaching-cum-referral center. Of these, 82% were males and 18% were females; 62% were smokers and 38% were non-smokers; 60% of patients belonged to the age group 41-60 years.
Endoscopic appearances were classified as: nodular mass 47%, polypoid mass 20%, malignant ulcer 10%, infilterative lesion 8%, rounded tumor mass 8%, linitis plastica 5% and 'early carcinoma' 2%. On histopathological typing; 79% of the lesions were adenocarcinomes, 8% mucoid carcinomas, 8% leiomyosarcomes, 4% schirrous carcinomas, and 1% reticulum cell sarcomas.
The possible etiological factors peculiar to the dietary constituents, including the consumption of hot salted tea and of a particular leafy vegetable, are singled out. The genetic factors may have an important role in the etiology of stomach cancer in this high risk group.
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