Prevention, Diagnosis and Treatment of Neonatal Herpes Simplex Virus Infections: A Review

Shehla H Naqvi



Herpes simplex virus (HSV) infections of the neonate are associated with very high mortality and survival frequently carries neurologic sequelae. The infection is generally acquired from infected maternal genital tract. The risks of neonatal HSV infection have become magnified by the recent increase in the incidence of genital herpes. Recognition of the high risk pregnant patient, detection of maternal genital herpes by culture or histopathology, followed by delivery of the child by cesarean section will prevent intrapartum exposure to infection. Treatment of neonatal herpes with adenine arabinoside and acyclovir significantly decreases the morbidity and mortality of the disease.


Herpes; Neonates; Diagnosis; Prevention

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