The Ultrasound Appearance of Early Periventricular Leukomalacia with Neuropathologic Correlates

  • Asma Q Fischer Medical College of Georgia, Augusta, GA, USA
  • Joseph C Anderson The University of Nebraska Medical Center. Omaha, Nebraska
  • Robert M Shuman University of Kentucky, Louisville, Kentucky
Keywords: Periventricular Leukomalacia, Ultrasound, Neonates

Abstract

DOI: http://dx.doi.org/10.5915/17-1-12734

Periventricular leukomalacia is a necrotic lesion of the cerebral white matter. It is seen in premature infants weighing 1000-1900 grams at birth, who have cardiorespiratory disturbances early in life and survive more than a week. It is characterized by necrosis of the periventricular axons adjacent to the lateral margins of the lateral ventricles. Premorbid recognition of this entity has been facilitated by the use of cranial ultrasound. Two types of lesions have been described sonographically: porencephalic and hemorrhagic. The former is anechoic and the latter hyperechoic; both are located periventricularly.

We present a third type of sonographic pattern associated with early. non-hemorrhagic periventricular leukomalacia. This sonographic pattern differs from those previously described. The cranial ultrasound and neuroropathologic findings will be presented in two premature infants.

Author Biographies

Asma Q Fischer, Medical College of Georgia, Augusta, GA, USA

Department of Neurology

The Medical College of Georgia, Augusta. Georgia

Joseph C Anderson, The University of Nebraska Medical Center. Omaha, Nebraska

Department of Radiology

The University of Nebraska Medical Center. Omaha, Nebraska

M.D.

 

Robert M Shuman, University of Kentucky, Louisville, Kentucky

Department of Pathology, University of Kentucky, Louisville, Kentucky

M.D.

Published
1985-01-15
Section
Case Reports