Clinical Overview of CRF in Children

A A Essalah


CRF Is the Irreversible deterioration of renal function that gradually progresses to end-stage renal disease. ESRD is severe CRF to the point at which homeostasis and patient survival cannot be maintained without renal replacement therapy or transplantation. Symptoms of CRF are usually when GFR is between 10 to 15% of normal. Children with CRF may suffer from failure to thrive, growth retraction, renal osteodystrophy, acidosis and anemia. Management of CRF aims at retarding the progression of renal damage, replacement therapy and treatment of complications. Growth retardation is a unique and consistent feature of CRF in children.


Chronic renal failure; End stage renal disease

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