Norfloxacin in Multiple Drug Resistant Typhoid Fever

Authors

  • M A Kamili Government Medical College and S.M.H.S. Hospital Srinagar Kashmir India
  • M Y Shah Government Medical College and S.M.H.S. Hospital Srinagar Kashmir India
  • Gazanfar Ali Government Medical College and S.M.H.S. Hospital Srinagar Kashmir India
  • R L Koul Government Medical College and S.M.H.S. Hospital Srinagar Kashmir India
  • Aejaz Aziz Government Medical College and S.M.H.S. Hospital Srinagar Kashmir India
  • G Q Allaqaband Government Medical College and S.M.H.S. Hospital Srinagar Kashmir India
  • Altaf Hussain Government Medical College and S.M.H.S. Hospital Srinagar Kashmir India

DOI:

https://doi.org/10.5915/23-1-14378

Keywords:

Salmonella typhi, Norfloxacin, Multiple Drug Resistance

Abstract

DOI: http://dx.doi.org/10.5915/23-1-14378

This study was undertaken to assess the efficacy of Norfloxacin and oral quinolone in multiple drug resistant salmonella typhi infections in 45 patients. All these patients received 800 mg of Norfloxacin daily for a period of two weeks. All patients had positive blood cultures for salmonella typhi and 30 patients had, in addition, high and rising titers of TO and TH antigen (>1:160).

All patients responded from day 4 to day 10 of Norfloxacin therapy. A follow-up of one year did not reveal any relapse or a carrier state in the studied group. We recommend use of Norfloxacin in chloramphenicol resistant salmonella typhi infections.

Author Biographies

M A Kamili, Government Medical College and S.M.H.S. Hospital Srinagar Kashmir India

Government Medical College and S.M.H.S. Hospital
Srinagar
Kashmir
India

M.D., M.Y.

M Y Shah, Government Medical College and S.M.H.S. Hospital Srinagar Kashmir India

M.D.

Government Medical College and S.M.H.S. Hospital
Srinagar
Kashmir
India

Gazanfar Ali, Government Medical College and S.M.H.S. Hospital Srinagar Kashmir India

M.D.

Government Medical College and S.M.H.S. Hospital
Srinagar
Kashmir
India

R L Koul, Government Medical College and S.M.H.S. Hospital Srinagar Kashmir India

M.D.

Government Medical College and S.M.H.S. Hospital
Srinagar
Kashmir
India

Aejaz Aziz, Government Medical College and S.M.H.S. Hospital Srinagar Kashmir India

M.D.

Government Medical College and S.M.H.S. Hospital
Srinagar
Kashmir
India

G Q Allaqaband, Government Medical College and S.M.H.S. Hospital Srinagar Kashmir India

F.R.C.P.

Government Medical College and S.M.H.S. Hospital
Srinagar
Kashmir
India

 

Altaf Hussain, Government Medical College and S.M.H.S. Hospital Srinagar Kashmir India

M.B.B.S.

Government Medical College and S.M.H.S. Hospital
Srinagar
Kashmir
India

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Published

1991-01-01

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Section

Original Articles