Corticosteroid induced, HHV-8 positive Kaposi’s sarcoma in a non-HIV elderly patient

Gh Mohiuddin Wani, Sheikh Manzoor Ahmad, Seema Qayoom, Bilquees Khursheed, A. R. Khan



Kaposi’s sarcoma (KS) was first described in 1872 by Moritz Kaposi. In 1994, Chang et al. first identified DNA sequences corresponding to human herpesvirus-8 (HHV-8) in AIDS-associated Kaposi sarcoma biopsies. It is now believed that presence of HHV-8 is necessary but not sufficient to cause KS. Other factors like immunosuppressive therapy also play a role. We describe an HIV-negative elderly patient who developed KS of skin and mucous membrane after prolonged use of corticosteroids for knee pain. The patient was positive for HHV-8.


Kaposi sarcoma, corticosteroids, HHV-8, HIV/AIDS

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