Corticosteroid induced, HHV-8 positive Kaposi’s sarcoma in a non-HIV elderly patient

Gh Mohiuddin Wani, Sheikh Manzoor Ahmad, Seema Qayoom, Bilquees Khursheed, A. R. Khan

Abstract


DOI: http://dx.doi.org/10.5915/44-1-9317

Kaposi’s sarcoma (KS) was first described in 1872 by Moritz Kaposi. In 1994, Chang et al. first identified DNA sequences corresponding to human herpesvirus-8 (HHV-8) in AIDS-associated Kaposi sarcoma biopsies. It is now believed that presence of HHV-8 is necessary but not sufficient to cause KS. Other factors like immunosuppressive therapy also play a role. We describe an HIV-negative elderly patient who developed KS of skin and mucous membrane after prolonged use of corticosteroids for knee pain. The patient was positive for HHV-8.


Keywords


Kaposi sarcoma, corticosteroids, HHV-8, HIV/AIDS

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DOI: http://dx.doi.org/10.5915/44-1-9317

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